Duratia 90mg (Dapoxetine)
Premature ejaculation occurs when a man ejaculates sooner than he or his
partner wants to. It is an uncontrolled ejaculation that may happen
before, during, or shortly after penetration, despite minimal
Premature ejaculation is among the common sexual complaints of men. About 1 in 3 men experience this problem. Premature ejaculation occurs when a man ejaculates sooner than he or his partner wants to. It is an uncontrolled ejaculation that may happen before, during, or shortly after penetration, despite minimal stimulation. While men can feel ashamed about this problem, options are available to treat this condition. Counselling, sexual techniques, medications or combination of these can help improve this sexual problem.
Duratia 90 is one of the drugs available in the market that can help treat premature ejactulation. It contains 90mg of the active ingredient Dapoxetine. Dapoxetine is an antidepressant drug that has been found to be effective in treating premature ejaculation. This drug is a selective serotonin reuptake inhibitor that works by increasing the levels of serotonin in body. Low levels of serotonin results in poor control over ejaculation. The drug increases serotonin levels and activity to help improve control over ejaculation and increases the time it takes to ejaculate.
Duratia is manufactured by Centurion Laboratories Pvt. Ltd.
The recommended dose of Dapoxetine is 30mg. A physician may adjust the dose depending on the patient’s response and tolerance to the drug.
A tablet of Duratia must be taken orally, 1 to 3 hours before an anticipated sexual activity. The tablet must be swallowed whole to avoid the tablet’s bitter taste, with a glass of water. It may be taken with or without food. This medicine must be taken only once every 24 hours as needed. It is not intended for daily use.
Duratia should only be used by men aged 18 to 64 years.
Duratia is contraindicated to patients with known allergy to the active ingredient, Dapoxetine and any of the tablet’s inactive ingredients.
This medication is also contraindicated to patients with the following medical conditions:
- Heart problems like heart failure, angina, heart valve problems
- History of heart attack
- History of fainting
- History of bipolar disorder, mania, hypomania, severe depression
- Psychiatric problem such as schizophrenia
- Uncontrolled epilepsy
- Severe kidney impairment
- Moderate to severe liver impairment
Duratia is contraindicated to patients taking the following medications:
- Recreational drugs
- Monoamine oxidase inhibitors
- SNRI and SSRI antidepressants
- Tricyclic antidepressants
- St. John’s wort
- Triptans for migraine
Each person taking Duratia will react differently to the drug. The following side effects are associated with the use of Duratia.
These side effects commonly affect about 1 out of 10 people:
- Dizziness or lightheadedness
- feeling sick, sweaty or confused – which may also be signs that fainting may occur
Duratia may cause blood pressure to drop that may make one dizzy or faint. These side effects may be avoided by taking the tablet with a glassful of water and standing up slowly from long periods of sitting or lying position. If the symptoms start to appear, sit or lie down until the symptoms pass. The drug must not be taken when dehydrated.
Taking of Duratia must be stopped and medical help must be sought immediately if these symptoms occur:
- Faints when standing up
- Changes in mood
- Thoughts of suicide or harming one’s self
Other side effects associated with Duratia include:
- Anxiety, agitation, irritability
- Difficulty sleeping
- Difficulty concentrating
- Reduced libido
- Feeling tired or sleepy
- Erectile dysfunction
- Nasal congestion
- Ringing in the ears
- Blurred vision
- Gastrointestinal disturbances
Rare side effects include:
- Suddenly falling asleep
- Urgent need in emptying bowel
- Dizziness after exertion
Warnings and Precautions
Driving, operating hazardous machineries or doing any unsafe tasks must be avoided while taking this medication until it is known how the body reacts to the drug or how the drug affects performance.
Duratia must be used in caution to patients with the following medical conditions:
- Mild to moderate kidney impairment
- Mild liver impairment
- History of low blood pressure
- Erectile dysfunction
- History of bleeding disorder or clotting problems
- At risk or have high pressure in the eye
- Dehydration due to diarrhea, vomiting, excessive sweating and other factors
Duratia may interact with the following medications. Caution must be observed.
- Blood thinners such as warfarin
- Alpha-blockers, nitrates, and some drugs for blood pressure and chest pain
- Some antifungals
- Non-steroidal anti-inflammatory drugs
- Some HIV medications
- Some antibiotics
- Medicines for mental health problems
Duratia and Alcohol
Drinking alcohol must be avoided while taking Duratia for it may worsen side effects such as dizziness, drowsiness, and difficulty in concentrating. It may also increase the risk of injury from fainting and from other side effects.
Duratia and Grapefruit
Caution is advised when consuming grapefruit and grapefruit juice as it mildly affects the absorption and clearance of Dapoxetine.